Methylene Violet 3RAX

Research use only, not for human use.

Methylene Violet 3RAX, a phenazine dye, is utilized for staining cell mitochondria and has the capability to alter DNA's molecular structure, disrupt DNA modules, and promote reactive singlet oxygen generation.

Methylene Violet 3RAX is a phenazine dye to stain the mitochondria of cells. Methylene Violet 3RAX can change the molecular structure of DNA, undermine the module of DNA, and induce the generation of the reactive singlet oxygen. Methylene Violet 3RAX shows inhibition for human erythrocyte AChE and human plasma BChE with an Kis of 1.58, 0.51 μM, respectively. Methylene Violet 3RAX has the potential for the research of potential photosensitizers for mitochondrial targeting action in PDT (photodynamic therapy).

Methylene Violet 3RAX shows antitumor activity by cutting off DNA strands in tumour cell.Methylene Violet 3RAX (0-400 μM) significantly enhances cleavage of DNA with over 60% photocleavage activity towards DNA at 300 μM.

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Others

Other Targets

Others

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4569-86-2

378.9

C22H23ClN4

>98% (HPLC)

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N(CC)(CC)C1=CC=2[N+](=C3C(=NC2C=C1)C=CC(N)=C3)C4=CC=CC=C4.[Cl-]

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(-20℃)

With Ice Pack

≥ 2 years